The crash occurred on the eastbound side in the area of Exit 35 in the town of Oyster Bay just before 1:40 p.m. on Sunday, Sept. 20, state police said.
The crash involved a car and a motorcycle. The motorcyclist died at the scene, according to state police.
The Northern State Parkway was closed for several hours during the accident investigation.
The identity of the victim has not yet been released.
The collision is still under investigation and state police are asking anyone with any information to call 631-756-3300.
Check back to Daily Voice for updates.
Click here to follow Daily Voice Brentwood and receive free news updates.